PLUS™ is a commercially manufactured, pooled human platelet lysate that is safe and consistent for the rapid expansion of human cell cultures. PLUS™ products are made from large pools of transfusion grade human platelets sourced from FDA-registered/AABB accredited blood centers, negative for infectious diseases.
PLUS™ supports the culture of many human cell types, including mesenchymal stromal cells (MSCs) derived from multiple tissue sources (bone marrow, adipose, umbilical), dendritic cells, dermal fibroblasts, epidermal keratinocytes, T cells, NK cells, and endothelial cells.
PLUS™ supports the culture of many human cell types, including mesenchymal stromal cells (MSCs) derived from multiple tissue sources (bone marrow, adipose, umbilical), dendritic cells, dermal fibroblasts, epidermal keratinocytes, T cells, NK cells, and endothelial cells.
Features and Benefits
- Potent: Human derived product rich in growth factors, cytokine, and other proteins
- Xeno-free: Heparin-free and no requirements for heparin addition
- Safe: Extensive infectious disease testing on every platelet unit
- Efficient: Improved proliferation without loss of phenotype for numerous cell types such as mesenchymal stem cells (MSCs), adipose derived stem cells (ASCs), dendritic cells, fibroblasts, keratinocytes, natural killer cells, etc.
- Consistent: 50 – 100 L lot sizes with Minimal lot-to-lot variation
- Flexible: Availability of research grade and GMP grade allows seamless transition from research to clinical applications
- Economical: Lower cell therapy manufacturing costs by providing higher cell yield in shorter time
- Accessible: FDA DMF for PLUS™ for faster and easier incorporation in clinical trials
- Custom: Can custom manufacture into different packaging or volumes (e.g. 5 mL vials, 1000 mL bottles)